Relative efficacy of neomycin and ampicillin against urease producing organisms.

The efficacy of neomycin in hepatic encephalopathy was highlighted3 as early as in 1957. The azotemia associated with aome fonru; of severe liver diseaseS militates against the use of neomycin in these circumstances6-8. The usefulness of ampicillin has been reported and the antibiotic has been suggested to be a satisfactory substitute9•1o. However, no study has directly compared the efficacy of patients suffering from portal hyper· tension. The present study was under· taken to see the relative efficacy of ampicillin and neomycin in the treatment or hepatic encephalopathy cases on the basil of the sensitivity pattern of the urease producing organism~; isolated from their gut. Material 11111 Medlods